The Release Properties of the Mesoporous Materials SBA-15 and PHTS for their Use in the Controlled Release of Ibuprofen and Vancomycin

1. Introduction Mesoporous materials are emerging as new drug delivery systems. Drug-loaded particles appear suitable for controlled release and drug targeting. These particles may have a potential as drug carriers because they could be able to enhance the bioavailibilty of poorly absorbed drugs, entailing a lowering of the therapeutic dose. These particles could also be efficient for entrapping slightly water-soluble drugs. MCM-41 is a typical mesoporous templated silica and it presents nanosized pores that allow the inclusion of drugs. Therefore, this material has been largely studied as a potential drug delivery system and shows promising results [1-3]. A serious disadvantage of MCM-41 is its low stability.